In short
Both use calcium alpha-ketoglutarate in a sustained-release format with gender-specific formulations. Rejuvant carries the direct association with the most-cited human analysis. SDAI BioAge is formulated and distributed for Asian markets with additional cofactors. Neither has a randomised controlled trial behind it.
Ownership disclosure. This site is operated by the SDAI BioAge™ brand. SDAI BioAge™ is one of the products compared below. We have written the comparison to be useful anyway, including SDAI's own limitations, because a comparison that only flatters its owner is worth nothing to you and you would spot it in a minute. Verify specifications against current product labels before buying anything, including ours.
These two products occupy the same corner of the category: premium price, sustained-release delivery, separate formulations for men and women. If you have decided the sustained-release argument is worth paying for, this is usually the comparison you end up making.
Side by side
| SDAI BioAge™ | Rejuvant | |
|---|---|---|
| Active compound | Calcium alpha-ketoglutarate | Calcium alpha-ketoglutarate |
| Delivery | Sustained release | Sustained release |
| Gender-specific formulas | Yes, differing cofactors | Yes, differing cofactors |
| Additional ingredients | B-group vitamins, folate, vitamin A, vitamin D3 | Cofactors differ by formula; check current label |
| Direct study association | No published study on this specific product | The product used in the 2021 retrospective analysis |
| Primary market focus | Asia-Pacific, with formulation aimed at regional dietary patterns | United States and international |
| RCT evidence | None | None |
The evidence question, handled properly
The honest differentiator here is study association, and it is worth being precise about how much weight it carries.
Rejuvant is the product involved in the 2021 retrospective analysis that reported an average reduction of around eight years in DNA methylation age across 42 people. That is the study quoted throughout this category, frequently by brands that had nothing to do with it.
Rejuvant's genuine claim is direct association with that analysis. The countervailing point is what the analysis was: retrospective, uncontrolled, self-selected participants, a single commercial methylation assay, and a commercial connection to the product. Being the subject of a hypothesis-generating study is a real distinction. It is not the same as being clinically proven, and it would be misleading to present it that way.
SDAI BioAge™ does not have a published study on its own specific formulation. It should not claim the Rejuvant result as its own, and neither should any other Ca-AKG brand.
The claim to watch across this whole category. A specific year figure attached to a product as though it were an expected dosing outcome. The figures in circulation come from a small uncontrolled analysis or from observational association studies. Neither design supports a predicted result for an individual. This applies to every brand in the table above.
Where they genuinely differ
Formulation philosophy
SDAI adds a B-vitamin and micronutrient cofactor set, positioned around regional dietary patterns. Whether cofactor addition improves outcomes is not separately established, but it is a coherent formulation rationale rather than an arbitrary one.
Market and availability
The practical differentiator for most buyers in Singapore and Malaysia. Local availability affects shipping time, cost, and whether you are importing a product for personal use. Import rules are covered on our Singapore page and Malaysia page.
Documentation you can request
The question to put to either brand: can you supply a batch-specific third-party certificate of analysis and a dissolution profile demonstrating the release curve. Both are reasonable requests for a premium product, and the answer tells you more than any comparison table can.
How to decide
- If the study association matters most to you, Rejuvant is the product in the study. Understand what that study was.
- If you are in Asia-Pacific and want local supply, SDAI's regional distribution is the practical advantage.
- If cost is the driver, neither. Standard-release Ca-AKG delivers the same molecule for substantially less. See the full category comparison.
- If your fitness, sleep or body composition are not yet handled, neither, for now. Those levers are larger than anything in this comparison.
Product specifications and ordering for SDAI BioAge™ are on the official brand site.
Common questions
Is SDAI BioAge the same as Rejuvant?
No. They are separate products from separate companies. Both use calcium alpha-ketoglutarate in a sustained-release format with gender-specific formulations, which makes them structurally similar, but they differ in cofactors, distribution and study association.
Does the Rejuvant study apply to SDAI BioAge?
No. The 2021 retrospective analysis involved Rejuvant specifically. Results from one product's study do not transfer to another product, even one using the same active compound in a similar format.
Which is better value?
Compare cost per gram of calcium AKG delivered, after shipping and any import duty, not cost per bottle. For buyers in Asia-Pacific, local distribution can close a price gap that looks wide on the sticker.
Do either have randomised controlled trial evidence?
No. Neither product has a published randomised controlled trial reporting biological age outcomes. The category's human evidence is one small retrospective uncontrolled analysis plus observational associations.